https://www.selleckchem.com/pr....oducts/bardoxolone.h
There was no significant difference in the secondary structure between the native and released insulin. In vitro studies revealed that the hydrogel microparticles exhibited non-cytotoxicity and were transported across the Caco-2 cell monolayers mainly via the paracellular pathway. In order to examine the effectiveness of hydrogel-based sustained release microparticles in delivering insulin in vivo, we administered different insulin-loaded hydrogel microparticles to diabetic mice. In these studies, we found that the insulin-loaded hy
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