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In Italy, throughout the period 2011-2017, the incidence of IMD increased from 0.25 cases/100,000 inhabitants in 2011 to 0.33 cases/100,000 in 2017. Most cases after 2012 were brought on by non-B serogroups. The sheer number of situations in subjects elderly 25-64 many years increased steadily after 2012 (36 situations in 2011, 79 in 2017), mainly as a result of non-B serogroups, representing a lot more than 65% of instances in those aged 25+ years. Into the period from 2011 t