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One of the most significant problems because of its development arises from the very low all-natural abundance of 17O (0.04%), which implies that isotopic labeling is usually needed just before NMR analyses. However, 17O-enrichment protocols tend to be ugly in terms of cost, safety, and/or practicality, also for compounds as easy as steel oxides. Right here, we display exactly how mechanochemistry can be used in an extremely efficient means for the direct 17O isotopic labeling of a number of s-, p-

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