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In the present investigation, the main reason behind selecting cholic acid because the vital scaffold is based on the fact it offers a facially amphiphilic nature, which supplies sufficient chance to refine the amphiphilicity by connecting the amino acid lysine. A complete of 16 book amphipathic cholic acid types were synthesized by sequentially linking lysine to C3-β-amino cholic acid methyl ester to steadfastly keep up the hydrophobic/hydrophilic

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