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Untreated ADHD in Adults Untreated ADHD can lead to many problems. These include financial issues, relationship issues, substance abuse, and criminal behavior. In fact, one study found that more than half of people who were sentenced to prison for crimes suffered from ADHD. Patients with untreated ADHD are also more likely to develop co-occurring mental health issues. These conditions can include depression and anxiety. Inadequate awareness Adults with untreated ADHD often don't know they have it, or