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© 2020 The Authors. The Kaohsiung Journal of Medical Sciences published by John Wiley Sons Australia on behalf of Kaohsiung Medical University.IMPORTANCE Primary angle closure glaucoma (PACG) is a major cause of irreversible visual impairment in Asia, but there is no published data on the effect of iStent on these patients. BACKGROUND To compare the efficacy and safety of combined phacoemulsification and iStent implantation with standard phacoemulsification in an Asian population. DESIGN A prospective, single-masked, randomized stud