https://www.selleckchem.com/pr....oducts/bay-k-8644.ht
An amendment to this paper has been published and can be accessed via a link at the top of the paper.Post-inflammatory behaviours in rodents are widely used to model human depression and to test the efficacy of novel anti-depressants. Mice injected with lipopolysaccharide (LPS) display a depressive-like phenotype twenty-four hours after endotoxin administration. Despite the widespread use of this model, the mechanisms that underlie the persistent behavioural changes after the transient peripheral inflammatory response remain elusive.
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