https://lurbinectedinmodulator.....com/effect-involvin
Model systems lacking of main components of caveolae, caveolins or cavins, didn't allow for an explicit attribution of observed functional flaws towards the dependence on caveolar invagination because they are lacking both invaginated caveolae and caveolin proteins. Knockdown studies in cultured cells and current knockout studies in mice identified an extra category of membrane-shaping proteins crucial for caveolar development, syndapins (PACSINs) - BAR domain superfamily proteins characterized by
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