https://www.selleckchem.com/EGFR(HER).html
inforce that moderate-to-severe TED is difficult to treat with an unmet medical need in the United States. Germline mutations in the succinate dehydrogenase genes ( / / / , -collectively, " " have been implicated in paraganglioma (PGL), renal cell carcinoma (RCC), gastrointestinal stromal tumor (GIST), and pituitary adenoma (PA). Negative SDHB tumor staining is indicative of SDH-deficient tumors, usually reflecting an underlying germline mutation. However, approximately 20% of individuals with SDH-deficient tumors lack an identifiable germlin
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