https://www.selleckchem.com/pr....oducts/Vorinostat-sa
Subjects with impaired fasting glucose, impaired glucose tolerance or any OGTT glucose concentration ≥200mg/dL were excluded. Cases (10.5y [8, 15]) exhibited reduced DI (p0.001) due to a simultaneous reduction in both φtotal (p0.001) and SI (p=0.008) compared to controls (11.5y [10.4, 14.9]). CL0 and CL180 were lower in cases than controls (p=0.005 and p=0.019). Pre-symptomatic Stage 1 T1D in youth is associated with reduced insulin sensitivity and lower β-cell responsiveness, and the presence of blunted insulin clearanc
Like
Comment
Share
