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These mucosal immune regulations are key to understanding the mechanisms underlying the development of gastrointestinal disorders. Here, we review recent advancements in our understanding of the role of gut metabolites in the regulation of gastrointestinal immunity, highlighting the cellular and molecular regulatory mechanisms by macronutrient-derived metabolites.Racket sports such as padel are characterized by the repetition of unilateral gestures, which can lead to negative adaptations like asymmetries or overuse musculoskeletal injuri