https://www.selleckchem.com/pr....oducts/oxythiamine-c
In kidneys from 5/6 nephrectomized rats, the expression of 13 miRNAs was significantly increased (1.5-fold, P 1.5-fold, P less then 0.05). Most of the deregulated miRNA species are implicated in endothelial-to-mesenchymal transition and inflammatory processes. Both telmisartan and linagliptin suppressed the induction of pro-fibrotic miRNAs, such as miR-199a-3p, and restored levels of anti-fibrotic miR-29c. In conclusion, the linagliptin and telmisartan-induced restorative effects on miR-29c expression we