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8 compared with claims (PDC 0.8. Of 459 patients returning the survey (response rate 43.5%), 50.1% were non-adherent in claims in month 12 while 20.9% were non-adherent based on the survey. Specificity of the 3-item metric for non-adherence was high (month 12 0.83). Sensitivity was relatively poor (month 12 0.25). Month 12 positive and negative predictive values were 0.59 and 0.52, respectively. A 3-item self-reported measure has high specificity but poor sensitivity for non-adherence versus claims in cardiometabolic disease. Desp