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3%) patients reached ESKD at a median time to ESKD of 84.8 (range 0.1-104.7) months. Both the eight- and four-variable KFRE models showed excellent predictive performance and discrimination (eight-variable C-index 0.872, 95% confidence interval [CI] 0.850-0.894, adequacy index 97.3%; four-variable C-index 0.874, 95% CI 0.852-0.896, adequacy index 97.9%). There was no incremental improvement in the prediction ability of the eight-variable model over the four-variable model in this cohort. The KFRE was validated in a multi-ethnic Singapore C
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