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What is the Best Treatment For ADHD in Adults? Most people with ADHD benefit from a combination of treatments. These treatments are usually multimodal and may include medication, therapy and lifestyle changes. Stimulants are the most popular treatments for ADHD. Finding the right dosage and balancing the side effects can be a trial and error procedure. Atomoxetine, an unstimulant FDA approved has no abuse potential associated with stimulants. It can be taken by mouth. Medication Adults with ADHD tend to be treated first by medication. Certain medica