https://www.selleckchem.com/pr....oducts/idasanutlin-r
This confirmed the absence of mutagenic activity in this test system. Exogenous metabolic activation did not modify these observations; suggesting that no metabolites with mutagenic activity were present. The endpoint of carcinogenicity in rats were negative for LQM 919 (p less then 0.05,) and LQM 996 (p less then 0.001). The results of the present study strongly suggest that ethyl-carbamates do not represent a risk for cancer in mammals.Methemoglobinemia results from increased amounts of oxidized hemoglobin in the blood w
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