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The RAIL approach offers a simple and novel strategy for site-selective labeling and control of RNAs, potentially of any length and origin.Lignin has a complicated three-dimensional structure that is different from other synthetic and bio-based materials. In this work, we first examined the physicochemical behavior, i.e., apparent hydrodynamic radius (Rh) and ζ-potential, of carboxymethylated lignin (CM) in a saline system. Then, the detailed interaction and adsorption behavior of CM on a cationic poly(diallyldimethylammonium chloride) (P
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