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To explore whether self-efficacy has any positive or negative mediating effects between family functioning and quality of life among elders with chronic diseases. A cross-sectional study. Questionnaires were collected from 516 community-dwelling elderly individuals with chronic diseases using a convenience sampling method. The questionnaires included the Self-efficacy for Managing Chronic Disease Six-Item Scale, the Family Adaptation Partnership Growth Affection Resolve Index and the MOS 36-Item Short Form Health Survey. Family functio
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