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Resonance ROA appears then as a useful selective indicator of the helical sense of poly(phenylacetylene)s, especially for those showing an extra Cotton band in the ECD spectrum. In these cases, a wrong helical sense is assigned based on ECD, while ROA alerts of this misassignment. © 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.A previous study reported that compound 5A, a caffeic acid phenethyl ester (CAPE) analog, exhibited obvious neuroprotective activity, in particular, compound 5A possessed higher stability and membrane permea

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