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To evaluate demographic trends of open globe injuries (OGIs) using a large dataset representative of United States population. Retrospective cross-sectional observational study using theNational Inpatient Sample (NIS) database from 2002 to 2013. Only patients witha primary admitting diagnosis of OGI wereincluded. Data included age (in years), gender, race, type of OGI, death rate and length and cost of stay. During the 12-year period, 27,467 adults (age 2 with acute OGIswere admittedtotheUS hospitals.Theincidence ofOGIs in the ad