https://www.selleckchem.com/
Papaverine is a benzylisoquinoline alkaloid from the plant Papaver somniferum (Opium poppy). It is approved as an antispasmodic drug by the US FDA and is also reported to have anti-cancer properties. Here, Papaverine's activity in chronic myeloid leukemia (CML) is explored using Saccharomyces cerevisiae, mammalian cancer cell lines, and in silico studies. The sensitivity of wild-type and mutant (anti-oxidant defense, apoptosis) strains of S. cerevisiaeto the drug Papaverine was tested by colony formation, spot assays, and AO/EB staining. In vitro cytotoxic
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