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Tabes dorsalis is a slowly progressive parenchymatous degenerative disease of the dorsal column and dorsal root of the spinal cord as a result of syphilis caused by infection with Treponema pallidum pallidum, one of three subspecies of Treponema pallidum that can cause sexually transmitted disease in humans. It generally occurs in the late tertiary stage of syphilis, but early involvement is reported. It may be accompanied by meningitis or meningomyelitis. Although CSF invasion often occurs early in syphilis, the clinical syndrome of tabes
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