https://www.selleckchem.com/
Treatment with N-acetylcysteine, an antioxidant and glutathione biosynthesis precursor, effectively blocked both dieldrin-induced increases in iROS and its inhibition of poly IC-induced upregulation of IFIT and MX gene expression, suggesting a role for intracellular oxidative status in dieldrin's modulation of anti-viral gene expression. This study demonstrates that dieldrin modulates key genes of the cellular innate immune responses that are normally involved in the host's cellular defense against viral infections. Our findings have potential relevance to
Like
Comment
Share
