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015). Multiple linear regression analysis showed that nCBF was negatively associated with carotid β-stiffness index (B = -0.822, P 0.001); CVR was positively associated with carotid systolic pressure (B = 0.001, P 0.001) after adjustment for age, sex, body mass index, and MCI status. These findings suggest that carotid artery stiffening may contribute at least in part to the reduced nCBF and increased CVR in patients with MCI associated with augmented carotid arterial pulsatility. These findings suggest that carotid artery stif