https://www.selleckchem.com/pr....oducts/Vorinostat-sa
Protein aggregates can sequester RNA in neurodegenerative disease, but the exact RNAs sequestered by tau inclusions have remained uncharacterized. In this issue of Neuron, Lester et al. (2021) begin to identify these RNAs and reveal related perturbations in nuclear speckles.Wang et al. (2021) characterize the molecular, cellular, and circuit-level role of Oligophrenin-1 in prefrontal parvalbumin interneurons, demonstrating that loss of Ophn1 function in these neurons is a mechanism for increased susceptibility to stress in intel
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