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chronic pain, a common complaint among older adults, affects physical and mental well-being. While opioid use for pain management has increased over the years, pain management in older adults remains challenging, due to potential severe adverse effects of opioids in this population. we examined the association between opioid use, and changes in cognitive function of older adults. prospective study. community dwelling older adults. study population consisted of 2,222 individuals aged 65-69years at baseline from the Personality and Tota