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The overall probability of an uneventful therapy continuation was 76.3% and 58.8% at 5 and 10 years, respectively. There was a significant increase in ejection fraction/fractional area of change (P less then 0.001) mainly attributable to patients with systemic left ventricle (P=0.002) and decrease in systemic ventricular end-diastolic dimensions (P less then 0.05) after CRT. New York Heart Association functional class improved from a median 2.0 to 1.25 (P less then 0.001). Long-term CRT response was present in 54.8% of patients at last follow-up and

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