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Adult ADHD and Comorbid Disorders Many adults with ADHD also suffer from comorbid disorders such as major depressive disorder (Kessler and colleagues, 2006). Many patients do not respond to medication for depression and may benefit from psychotherapy. Treatments that are most effective in reducing core symptoms of ADHD appear to increase and balance levels of specific neurotransmitters in the brain. Stimulants such as methylphenidate and amphetamine are commonly prescribed. Medicin
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