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OBJECTIVE The postpartum period is a vulnerable time for sexual health, yet the relationship between biopsychosocial factors and sexual function over time remains unclear. Our aim was to identify trajectories of postpartum sexual function in first-time mothers (N = 646) and examine associations with biopsychosocial factors. METHODS Biopsychosocial factors were assessed at delivery and 3 months postpartum. Sexual function was assessed during pregnancy, 3, 6, and 12 months postpartum using the Female Sexual Function Index. Latent class growth analysis