https://pdgfreceptor.com/sodiu....m-glucose-co-transpo
Substances 3b, 3h, 3g and 4h had minimal inhibitory effect on normal BJ1 cells indicating their particular security profile. Substances 3b and 4h in particular displayed more potent antiproliferative activity against HCT116 and MCF7, meanwhile compounds 3g, 3h and 4g revealed powerful to reasonable activity. Compound 3b had IC50 of 78.3 µM and 53.9 µM against HCT-116 and MCF-7 correspondingly with similar IC50 for doxorubicin of 65.1 µM and 45.
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