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Herein, we summarize previous findings concerning direct and indirect influences of sirtuin 1 manipulation on transplantation. Copyright © 2020 Sara Assadiasl et al.Objectives We sought to compare functional and cosmetic satisfaction among male and female patients undergoing open and closed septorhinoplasty within sub-groups of indications for the surgery at a tertiary care hospital in Oman. Methods We conducted a prospective study in the ear, nose, and throat surgery department at Sultan Qaboos University Hospital from