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Preeclampsia stays a challenge without a very good therapy. Evidence supports targetability of soluble fms-like tyrosine kinase-1 (sFlt-1) and dissolvable endoglin (sEng), that are circulated exceedingly through the placenta under ischemic and hypoxic stresses. We compared four trophoblast cell lines, BeWo, Jar, Jeg-3, and HTR-8/SVneo, in order to determine an appropriate design for medicine screening. Cultured trophoblasts had be

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