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g. age, gender), co-morbidities (e.g. cirrhosis, diabetes, steroid use), severity of injury [e.g. vital signs on arrival, mechanism, injury severity scale (ISS)], and operative and angiographic interventions. RESULTS Of 1,002,595 patients, 37,568 were included. The mean age was 42±18.6 years, 74.6% were males, 68% had blunt trauma, and median ISS was 25 [17-34]. Adjusting for all available confounders, odds of INF increased incrementally from 1.00 (reference, 0-2 units) to 1.23 (95% CI 1.11-1.37) for 4 units transfused to 4.89 (95% CI
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