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Besides paid off salinity, river-lake methods have calcium levels less than seawater. Cell adhesion in sponges is mediated by calcium-dependent multivalent self-interactions of sulfated polysaccharides components of membrane-bound proteoglycans called aggregation elements. Cells of marine sponges require seawater average calcium concentration (10 mM) to sustain adhesion promoted by aggregation facets. We prove right here that the freshwater sponge Spongilla alba can thrive in a calcium-poor aquat
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