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outcomes, at 5 years after surgery. ClinicalTrials.gov (NCT01052233 and NCT00549172). ClinicalTrials.gov (NCT01052233 and NCT00549172).We asked whether the physiological and morphologic properties of hypoglossal motor neurons (CNXII MNs) that innervate protruder or retractor tongue muscles are disrupted in neonatal LgDel mice that carry a heterozygous deletion parallel to that associated with DiGeorge/22q11.2 deletion syndrome (22q11.2DS). Disrupted coordination of tongue movement in LgDel mouse pups may contribute to suckling, feeding,