https://www.selleckchem.com/pr....oducts/reversine.htm
An amendment to this paper has been published and can be accessed via a link at the top of the paper.Transcription is regulated through a dynamic interplay of DNA-associated proteins, and the composition of gene-regulatory complexes is subject to continuous adjustments. Protein alterations include post-translational modifications and elimination of individual polypeptides. Spatially and temporally controlled protein removal is, therefore, essential for gene regulation and accounts for the short half-life of many transcription factors.
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