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To assess differentiating features between bacterial, , and skull base osteomyelitis (SBO) with regard to clinical presentation and imaging appearances. A literature search was performed in April 2020 for studies on SBO with a minimum sample size of 10 patients. Studies that reported presenting symptoms, cross-sectional imaging findings, complications, and mortality were included in the analysis. The quality of included articles was tested using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. A data extraction form was use

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