https://www.selleckchem.com/pr....oducts/elamipretide-
YafQ is an endoribonuclease toxin that degrades target gene transcripts such as that of tnaA, a gene encoding tryptophanase to synthesize indole from tryptophan. DinJ is the cognate antitoxin of YafQ and YafQ-DinJ system was reported to regulate persister formation by controlling indole production in Escherichia coli In this study, we investigated the role of YafQ-DinJ, indole production, and persister population in bacterial heat tolerance. Single-gene knockout mutants of yafQ (ΔyafQ), dinJ (ΔdinJ), and tnaA (ΔtnaA) showed
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