https://gw4869.com/index.php/c....ompound-info-upon-as
A genome-wide connection study (GWAS) ended up being performed on 2,597 kiddies in the Children's Oncology Group (COG) AALL0232 test for high-risk B-ALL. Association between genotype and end-of-induction MRD levels ended up being evaluated for 863,370 solitary nucleotide polymorphisms (SNPs), adjusting for genetic ancestry and therapy strata. Top variants had been additional evaluated in a validation cohort of 491 customers through the COG P9905/6 each studies. The separate prognostic value of SNPs had been d