https://ubiquitininhibitors.co....m/large-term-regardi
We hypothesized that there can be a non-linear association between bTMB and survival. This study used the medical and genetic data from POPLAR (n = 105, instruction set) and OAK (n = 324, validation ready) studies. The non-linear organization between bTMB and survival ended up being evaluated using limited cubic spline (RCS). The cutoff values for bTMB were calculated via X-tile software. Non-linear interactions were observed between bTMB and PFS and total success (OS) in RCS plots (both P n