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The prihma in Japanese patients ≥ 40 years versus those less then 40 years old, our outcomes demonstrated greater clinical and financial burden in elderly versus more youthful patients.The impact of inhibition associated with the cyst suppressor p53 on the anti-oxidant system genetics appearance under the influence of cytotoxic substances of this platinum group ended up being studied. It had been found that the action of platinum(II) and platinum(IV