https://www.selleckchem.com/pr....oducts/BafilomycinA1
Intracellular uptake of BPA was 1.5-5.0 times greater among the clones than that in a control clone. The LAT1-overexpressing clones and transiently LAT1-lipofected T98G cells showed clearly enhanced sensitivity to neutron and γ-ray fluences compared to the control clone when they were treated with 10BPA. The sensitivity of cancer cells to the fluences was well correlated with the expression level of LAT1 in the cells and the level of BPA uptake. These results suggest that overexpression of LAT1 in cancer cells results in enhanced
Like
Comment
Share
