https://www.selleckchem.com/pr....oducts/gsk1016790a.h
Down-regulated miR-195-5p and up-regulated CXCR4 ameliorated cardiac function, abated inflammatory factors contents, oxidative stress reaction and myocardial enzyme indices in HF mice. Down-regulated miR-195-5p and up-regulated CXCR4 suppressed apoptosis of cardiomyocytes in HF mice. CONCLUSION Depleting miR-195-5p and up-regulating CXCR4 alleviates cardiac function injury in mice with HF via inhibition of JAK/STAT signaling pathway activation. MiR-195-5p might be a potential candidate marker and therapeutic target for HF. V.The dev
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