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Our subgroup analysis suggested that a maximum dose of 4 g/d might have homocysteine-lowering effects without any adverse effect on lipid profiles reported with doses of ≥4 g/d. In conclusion, the present systematic review and meta-analysis supports the advantage of a lower dose of betaine supplementation ( less then 4 g/d) on homocysteine concentrations without the lipid-augmenting effect observed with a higher dosage.The purpose of this study was to describe nurses' perceptions about the use of interpersonal touch in their clinical pr
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