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Median t1/2 was 2 h and median AUC0-last was 364 µg h/ml both for IV and IM administration. Median Cmax after IM administration ended up being 101 µg/ml, with a median Tmax of 0.7 h. Relative bioavailability of IM injection had been 90%. There were no statistically considerable differences between estimated IV and IM pharmacokinetic parameters. Plasma concentrations remained above the human CLSI prone breakpoint for Enterobacteriaceae for over 8 h following IV an

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