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We investigate the frequencyand diagnostic yield of cerebrospinal fluid (CSF) analysis in adult patients with status epilepticus (SE)and itsimpact on the outcome. From 2011 to 2018, adultpatients treated at the University Hospital Basel were included. Primary outcomes were defined as the frequency of lumbar puncture and results from chemical, cellular, and microbiologic CSF analyses. Secondary outcomes were differences between patients receiving and not receiving lumbar puncture in the context of SE. In 18% of 408 patients, a lumbar punc