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Increased cGMP hydrolysis in light-exposed conditions compared to that in dark conditions was observed. After the subretinal injection in the rats, preservation of optokinetic responses was noted up to 20 weeks, while electroretinographic response decreased. Survival of the injected cells was confirmed with positive immunofluorescence staining of human markers at 8 weeks. Cells showed photoreceptor-specific features when stem cell-derived neurogenic precursors were cocultured with RPE cells. Cells showed photoreceptor-specific features
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