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Predicated on all the above, a RP-HPLC method was developed and validated for the quantitative evaluation of these two substances in I. sonorae root extracts obtained with various extraction conditions. In the present study, the quantitative evaluation of kinoin B diglycoside in every the extracts was done also. As a result, no direct correlation was found involving the antiproliferative activity (IC5 against real human cervical disease cell range (HeLa) plus the structure associate

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