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During a mean follow-up of 58.3 ± 38.1 months (range 0-121months), the 5-year overall survival and disease-free survival rates were 56.1% and 53.0% for LAG, and 57.7% and 50.9% for OG. In the subgroup analysis for AGC, laparoscopy-assisted distal gastrectomy and total gastrectomy did not result in inferior long-term outcomes, and recurrence was found in 49 patients (31.2%). Age more than 65years and the advanced tumor stage were independent risk factors of survival. LAG is a feasible and safe treatment for gastric cancer, with good onc