https://apilimodinhibitor.com/....water-sanitation-alo
Earlier studies have shown that N-terminal areas of the AAV capsid proteins have the effect of endosomal escape and atomic trafficking, but the components remain unidentified. We identified a highly-conserved three-residue serine/threonine (S/T) theme into the capsid N-terminus, formerly uncharacterized in its part in intracellular trafficking and transduction. Making use of alanine checking mutagenesis, we found S155 plus the flanking deposits, D154 and G158, are necessary for AAV2 transduc
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